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1 USD = 3.9676 PLN
10 USD = 39.676 PLN
100 USD = 396.76 PLN
1000 USD = 3967.6 PLN
10000 USD = 39676 PLN
Informationen werden zu Informationszwecken und nicht zum Handel oder zur Beratung, und kann sich leicht verzögern.
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Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated . . . Poly (adenosine diphosphate–ribose) polymerase inhibitors target cancers with defects in homologous recombination repair by synthetic lethality New therapies are needed to reduce recurrence in
OlympiA: Game Changer for Breast Cancer Treatment | NEJM . . . For patients receiving adjuvant chemotherapy, high risk was defined as TNBC stage ≥pT2 or ≥pN1 or ER positive with ≥4 positive nodes Most patients (94%) received an anthracycline taxane
Table 7, Details of the OlympiA Study - Olaparib (Lynparza . . . There were 2 exceptions The first was adequately treated nonmelanoma skin cancer, curatively treated in situ cancer of the cervix, DCIS, or stage I grade 1 endometrial carcinoma
OlympiA: A phase III, multicenter, randomized, placebo . . . Eligible pts with TNBC had ≥pT2 or ≥pN1 disease prior to ACT or non-pCR after NACT; those with HR+ BC had ≥4 positive nodes prior to ACT or non-pCR and CPS EG score ≥3 after NACT
Clinicopathological characteristics and eligibility for . . . In this study, we sought to characterize the real-world proportion of gBRCA1 2 PV carriers eligible for adjuvant olaparib according to the OlympiA criteria, and to compare clinicopathologic
OlympiA: A randomized phase III trial of olaparib as adjuvant . . . Pts with hormone receptor (HR) positive BC must have ≥4 positive lymph nodes in the adjuvant and non-pCR and CPS EG score ≥3 in the neoadjuvant setting Pts must also harbor a deleterious gBRCAm
LBA1 Plenary Session OlympiA: A phase III, multicenter . . . Eligible pts with TNBC had $pT2 or $pN1 disease prior to ACT or non-pCR after NACT; those with HR+ BC had $4 positive nodes prior to ACT or non-pCR and CPS EG score $3 after NACT